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Why Choose BeneFIX

Why BeneFIX?

The answer is easy — because you may want a product that’s convenient, effective, and has proven viral safety. Talk to your doctor about which Factor IX product may be right for you.

BeneFIX works

BeneFIX has proven viral safety and was proven effective in several important clinical trials. In some studies, BeneFIX was tested for its ability to prevent bleeds, and in others, for its ability to control bleeds once they started. The results add up to treatment that may work for you.

BeneFIX prevents bleeds

Clinical trials showed that BeneFIX prevented bleeds in both previously treated and previously untreated patients:

  • In previously untreated patients: 27 of 32 patients experienced no spontaneous bleeding (bleeding not caused by injury) within 48 hours of infusion with BeneFIX
  • In previously treated patients: 65% of patients (11 of 17) had no spontaneous bleeding while on a preventive regimen with BeneFIX

BeneFIX controls bleeds

Important studies also examined how BeneFIX worked in patients with spontaneous bleeding or bleeding caused by injury. In a study of 1,796 bleeding episodes in 55 previously treated patients with severe or moderate hemophilia B:

  • All bleeds were controlled
  • 9 out of 10 responses were rated “excellent” or “good”
  • Only 1 infusion was needed in most cases (81% of bleeds were controlled with only 1 infusion of BeneFIX)

BeneFIX offers peace of mind for patients
undergoing surgery

Ninety-seven percent (97%) of physicians and patients rated BeneFIX “excellent” or “good” for controlling bleeds both during and after surgery.

In 28 patients undergoing 36 surgeries:

  • All bleeds were controlled
  • No spontaneous bleeding was reported after surgery
 

Indication

BeneFIX is indicated for the control and prevention of hemorrhagic episodes in patients with hemophilia B (congenital factor IX deficiency or Christmas disease), including control and prevention of bleeding in surgical settings. BeneFIX is not indicated for the treatment of other factor deficiencies (eg, factors II, VII, VIII and X) nor the treatment of hemophilia A patients with inhibitors to factor VIII, nor the reversal of coumarin-induced anticoagulation, nor the treatment of bleeding due to low levels of liver-dependent coagulation factors.

Important Safety Information

  • As with the intravenous administration of any protein product, common adverse reactions may include headache, fever, chills, flushing, nausea, vomiting, or tiredness.
  • BeneFIX may be contraindicated in patients with a known history of hypersensitivity to hamster protein.
  • Allergic-type hypersensitivity reactions, including anaphylaxis, have been reported for all factor IX products. Patients should be informed of the early symptoms and signs of hypersensitivity reactions. Patients should discontinue use of the product and contact their health care provider immediately and/or seek emergency care if any hypersensitivity reactions occur.
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