BeneFIX is the FIRST and ONLY recombinant factor IX, with no human or animal plasma or albumin used in the manufacturing process.
Viral Safety Matters
How BeneFIX is manufactured
People with hemophilia B are missing a protein known as factor IX, which helps their blood to clot. To make BeneFIX, scientists produce this protein synthetically (outside of the body) using a process called recombinant technology.
The gene for factor IX was inserted into special production cells. The special production cells produce factor IX. The cells are multiplied to produce large amounts of the factor. The factor is later separated from the production cells, carefully purified, and dried. The result is the powder you see in BeneFIX vials — which can be reconstituted for your use.