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How to use BeneFIX

How should I store BeneFIX?
DO NOT FREEZE BeneFIX. Store BeneFIX in the refrigerator at 36° to 46°F (2° to 8°C). BeneFIX may also be stored at room temperature (below 77°F) for up to 6 months, until the expiration date.

If you store BeneFIX at room temperature,
be careful to write down the date you put BeneFIX at room temperature, so you know when to throw it out.

There is a space provided on the outer carton for you to write the date.

At the end of the 6-month period, the product should not be put back into the refrigerator, but should be used immediately or discarded. Freezing should be avoided to prevent damage to the prefilled diluent syringe.

Throw away any unused BeneFIX after the expiration date.

BeneFIX does not contain a preservative. After reconstituting BeneFIX, you can store it at room temperature for up to 3 hours. If you have not used it in 3 hours, throw it away.

Store the diluent syringe at 36° to 77°F
(2° to 25°C).

Do not use BeneFIX if the reconstituted solution is not clear and colorless.

Simple Preparation and Fast Reconstitution

Infusion directions for BeneFIX

These are general directions for using the BeneFIX Rapid Reconstitution (R2) Kit. Always follow the instructions provided by your health care provider.

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Please see the instructions for use in the BeneFIX Prescribing Information.

 

What Is BeneFIX?

BeneFIX is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital factor IX deficiency or Christmas disease.

BeneFIX is NOT used to treat hemophilia A.

Important Safety Information for BeneFIX

  • BeneFIX is contraindicated in patients who have manifested life-threatening, immediate hypersensitivity reactions, including anaphylaxis, to the product or its components, including hamster protein.
  • Call your health care provider right away if your bleeding is not controlled after using BeneFIX.
  • Allergic reactions may occur with BeneFIX. Call your health care provider or get emergency treatment right away if you have any of the following symptoms: wheezing, difficulty breathing, chest tightness, your lips and gums turning blue, fast heartbeat, facial swelling, faintness, rash or hives.
  • Your body can make antibodies, called “inhibitors,” which may interfere with the effectiveness of BeneFIX.
  • If you have risk factors for developing blood clots, such as a venous catheter through which BeneFIX is given by continuous infusion, BeneFIX may increase the risk of abnormal blood clots. The safety and efficacy of BeneFIX administration by continuous infusion have not been established.
  • Some common side effects of BeneFIX are nausea, injection site reaction, injection site pain, headache, dizziness and rash.